Xinwei Li, Zuo Chunyan, Mengcao Lu, Jiaxuan Wang, Wenjing Ren, Wei Shan, Qian Ren, Qun Wang
Familial Focal Epilepsy with Variable Foci 1 (FFEVF1) is an autosomal dominant epilepsy disorder characterized by focal seizures. Induced pluripotent stem cells (iPSCs) were derived from a 21-year-old epileptic patient carrying a heterozygous DEPDC5 c.2748 (C > G) (exon 29) variant. The derived iPSCs maintain a normal karyotype, express pluripotency markers, and retain the ability to differentiate into the three germ layers. iPSCs are for research use only, including scientific research and the development of anti-epileptic therapeutics.