Ke Tang, Tianshu Zheng, Hao Zhu, Fan Xu, Congcong Ma, Zhenhua Qi, Siyi Cao, Qiang Da, Ke Yan, Wencheng Wu, Yi Han, Liping Xie, Yan Zhang, Yong Ji
mice fed with high fat diet. Overall, SNO-HINT1 drives foam cell formation and atherosclerosis through reducing degradation of SR-A1 mediated by lysosome pathway and promoting CD36 transcription mediated by USF2. Our findings suggest that SNO-HINT1 can be a potential therapeutic target for atherosclerosis.