International Society of Pediatric Respiratory Diseases (INSPiRED) call to action: A Global Ban on Electronic Cigarette Sales to Protect our Children's Future.

Electronic cigarettes (e-cigarettes) have become a leading form of nicotine use among children and adolescents worldwide. The World Health Organization (WHO) estimates that approximately 15 million young teenagers currently use these products. Contrary to early claims regarding reduced harm, e‑cigarettes expose users to a range of toxic substances, including carcinogens and, increasingly, synthetic nicotine compounds and other psychoactive agents. Epidemiological studies associate adolescent e‑cigarette use with respiratory morbidity, adverse mental health outcomes, and a substantially increased likelihood of subsequent initiation of combustible cigarette smoking. Dual use of e‑cigarettes and conventional cigarettes, reported among more than one third of nicotine‑using high school students in the United States, is associated with greater health risks than use of either product alone. The rise in adolescent vaping has been influenced by social media promotion backed by tobacco companies, flavored products, low-cost disposable devices, and peer norms, alongside persistent misperceptions of harm. Global regulatory responses remain inconsistent, with limited adoption of comprehensive bans and continued challenges from illicit markets. The International Society of Pediatric Respiratory Diseases (INSPiRED) calls for a global ban of e-cigarettes sales, advertising bans, increased taxation, and development of cessation services for youth.