Samantha Conley, Stacy Al-Saleh, C. Robert Bennett, Heidi Lindroth, Natalie S. McAndrew, Melissa D. Pinto, Komal Singh, Cindy Tofthagen, Melissa Wilson, Linda L. Chlan
BACKGROUND: A conceptual framework that integrates symptom science and self-management science is necessary to drive evidence-based innovations in symptom self-management, thereby improving outcomes for individuals with complex health conditions. PURPOSE: The purpose of this paper is to describe the Symptom Self-Management Framework for Individuals with Complex Health Conditions. METHODS: In this paper, we describe the development process and framework components of the Symptom Self-Management Framework for Individuals with Complex Health Conditions. FINDINGS: The framework encompasses contextual factors (individual, interpersonal, institutional, and environmental factors) that influence symptoms and symptom self-management, which in turn impact health-related outcomes. DISCUSSION: We provide examples of how the framework is being applied by nurse scientists and include recommendations for future research and integration into practice. CONCLUSION: This framework can be used for the testing of symptom self-management interventions for individuals with complex conditions across various practice settings and patient populations.