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◆ Next Nanotechnology2026-02-06· Targeted drug delivery

Advancements in nanostructured drug delivery systems: Innovations in targeted therapy and multifunctional nanomaterials

Pavithran Kumar, Pasiyappazham Ramasamy, Manjunathan Jagadeesan

原始摘要(英文原文)· Original abstract
Recent advancements in nanotechnology have highlighted the potential of nanoparticles in medical applications. This is especially true for targeted drug delivery systems. Nanoparticles offer unique characteristics, such as stable ligand interactions, varied sizes and shapes, and high carrier capacities. These features make them ideal for carrying both hydrophilic and hydrophobic substances in disease therapy. Novel therapeutic nanostructures have shown promise in targeted drug delivery. They offer superior carrier capacity, specific targeting, and low toxicity. These advancements have led to significant improvements in stability and absorption efficiency. They also enhance the ability to reach cellular and intracellular targets with greater effectiveness. However, there are complex issues regarding toxicity, safety, and production scale of nanoparticles. Resolving these problems could lead to clinical treatments based on laboratory successes. The next generation of medication delivery systems could benefit from personalized therapeutic techniques combined with smart nanomaterials. The main aim of this review is to explore recent developments in the design, synthesis, and optimization of therapeutic nanoparticles. This includes understanding their size, shape, and multifunctional properties to enhance the effectiveness of drug delivery. This review covers various methods for designing and characterizing nanoparticles. It focuses on optimizing nanostructures for enhanced drug delivery. The synthesis techniques, analysis methods, and potential modifications of nanoparticle characterization are discussed. Properly synthesized and optimized therapeutic nanoparticles represent a significant breakthrough in the field of drug delivery systems. Their ability to overcome the limitations of traditional therapies holds promise for future medical applications. Further research into their characterization and development will enhance clinical relevance and ensure safe, effective use in therapeutic settings.
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