Saman Salaran, Salam Findakly, Samyak Shah, Kaiwen Cabbabe, Kim Quach, Michael Zhan, Panagiota Kakridas, Warren Clements, Matthew Lukies
Renal trauma is safely and effectively managed conservatively when clinically appropriate, including in patients with initial hemodynamic instability and high-grade injuries. Embolization provides a definitive, organ-sparing escalation strategy for ongoing hemorrhage, with encouraging renal function outcomes among patients with available data.
PURPOSE: To evaluate and compare renal injury patterns, management pathways, clinical outcomes, and renal function following renal trauma at a high-volume Level 1 trauma center.
METHODS: A single-center retrospective cohort study was performed. Patients aged ≥16 years with renal trauma over a 12-year-period were included. Data collected included injury mechanism, injury grade, hemodynamic status, and renal function. Primary management was classified as conservative, interventional radiology (embolization) and surgery. Outcomes included nephrectomy, 30-day mortality, and post-discharge renal function. Subgroup analyses were performed for hemodynamically unstable, high-grade injuries and embolization patient groups.
RESULTS: A total of 573 patients were included (median age 37 years [IQR 24-54]; 82% male). 537 patients (94%) were primarily managed conservatively, while 25 (4%) underwent primary embolization and 11 (1.7%) primary surgery. Nephrectomy was performed in four patients (0.7%). Thirty-day all-cause mortality was 2.3%, with renal trauma-specific mortality of 0.2%. Among hemodynamically unstable (n=123) and high-grade injuries (n=181) subgroups, conservative management was predominant with similar outcomes. Embolization demonstrated 100% technical success, was mostly selective or super-selective (88%), and resulted in low subsequent nephrectomy rate (3%). Renal function outcomes were encouraging among patients with available data, although interpretation is limited by capped eGFR reporting and incomplete follow-up.
CONCLUSION: Renal trauma is safely and effectively managed conservatively when clinically appropriate, including in patients with initial hemodynamic instability and high-grade injuries. Embolization provides a definitive, organ-sparing escalation strategy for ongoing hemorrhage, with encouraging renal function outcomes among patients with available data.