A scientometric study on research trends and characteristics of diabetes-associated periodontal disease.

BACKGROUND/PURPOSE: Substantial evidence demonstrates that diabetes is associated with periodontal disease. The purpose of this study was to analyze the scientometric characteristics and research trends of diabetes-associated periodontal disease (DAPD). MATERIALS AND METHODS: All the papers on DAPD were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2019 and after 2019 in the analysis of research trends. RESULTS: There were 2466 papers on DAPD, with total citations of 73,553 and the h index of 120. The trend of clinical investigations has highlighted periodontal examination, bone development, micro-computed tomography, tooth brushing, cardiovascular disease, hypertension, diabetic complication, diabetic periodontitis, drug therapy, fasting blood glucose level, gingival index, and questionnaire. The trend of laboratory investigations has changed to gene expression, macrophage, signal transduction, microbiota, microflora, RNA 16s, in vitro study, immune response, antioxidant, reactive oxygen metabolite, and interleukin (IL)-17 after 2019. There have always been common keywords such as tumor necrosis factor alpha, IL-1beta, IL-6, insulin resistance, C-reactive protein, osteolysis, Porphyromonas gingivalis, genetics, advanced glycation end-products, oxidative stress, and saliva. CONCLUSION: This scientometric study elucidated the current scenario and research trends of DAPD, particularly the comprehensive identification and recognition of the important research topics concerned. A better understanding of diabetic-periodontal relationship supports interdisciplinary approaches and points toward novel preventive and therapeutic strategies.