Yash Desai, Rohan Singh, Kush Desai, Samuel Bennett, Rohan Desai, Manu Mysore
5-Fluorouracil (5-FU), a chemotherapeutic agent, is routinely used for solid tumors. Known cardiotoxic effects of 5-FU include fatal arrhythmias, myocardial infarctions, and coronary vasospasms. This case report describes a 56-year-old man who had acute heart failure with cardiogenic shock suspected to be related to 5-FU exposure; notably, cardiac dysfunction resolved following cessation of therapy.