Zongzheng Zou, Xiuqing Qian, Jifeng Ren, Yuqing Wang, Yuqi Liu, Aojun Luo, Mengyuan Guo, Hui Tong, Ruiran Li, Shanshan Li, Haixia Zhang
-AP-1-PTGS2/PGE2 axis as a core mechanotransduction pathway driving corneal inflammation. Given the widespread expression of PIEZO1, our results provide mechanistic insight into how abnormal mechanical forces trigger inflammatory responses, highlighting a potential framework for understanding mechano-inflammation across tissues.