◆ iScience2025-11-22· Downregulation and upregulation
Network-based insights into miRNA regulation of β-cell insulin secretion in type 2 diabetes
Elaine Cowan, Alexandros Karagiannopoulos, Alessio Pollastri, Akira Asai, Mototsugu Nagao, Marlena Maziarz, Jonathan L.S. Esguerra, Lena Eliasson
原始摘要(英文原文)· Original abstract
and reduced expression of CADM1, a target of miR-101-3p. In summary, we have comprehensively identified miRNA-mRNA alterations in human islets associated with T2D pathogenesis and propose that miR-101-3p plays an important role in β-cell insulin secretion.