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◆ International Journal for Parasitology Drugs and Drug Resistance2026-03-18· Medicine

TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants

Claudia M. Rohr, Sang-Kyu Park, Kelsilandia Aguiar-Martins, Timothy J.C. Anderson, Duncan Berger, Matthew Berriman, Sarah K. Buddenborg, Amaya L. Bustinduy, Frédéric D. Chevalier, James A. Cotton, Thomas Crellen, Stephen R. Doyle, Aidan M. Emery, Julien Kincaid Smith, Safari Kinung'hi, Poppy H.L. Lamberton, Winka Le Clec’h, Eric M. Ndombi, Tom Pennance, Candia Rowel, Shannan Summers, John Vianney Tushabe, Martin Walker, Bonnie L. Webster, Joanne P. Webster, Shona Wilson, Jonathan S. Marchant

原始摘要(英文原文)· Original abstract
variants have been functionally profiled, where geographically these variants have been found, their frequency within populations, and their potential impact on PZQ sensitivity. The overall goal is to facilitate rapid community-wide exchange of data to monitor predicted variants of concern that are likely to be associated with decreased PZQ efficacy.
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TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants — 科研速览 Science Skim