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◆ International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2026-08-06

Persistent non-viable Plasmodium falciparum parasitemia mimicking artesunate treatment failure and unmasking functional hyposplenism.

Arthur Cornet, Jean-Marc Schwob, Camille Roussel, Romain Cordaillat, Christian Nsanzabana, Esther Kuenzli, Rosalie Zimmermann, Andreas Neumayr, Pierre Buffet, Gilles Eperon, Stefano Musumeci

原始摘要(英文原文)· Original abstract
A 40-year-old woman was admitted with severe Plasmodium falciparum malaria. Although she improved clinically under intravenous artesunate, parasitemia unexpectedly increased. Reassessment identified previously unrecognized functional hyposplenism, leading to delayed clearance of non-viable parasites and falsely suggesting artemisinin resistance.
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Persistent non-viable Plasmodium falciparum parasitemia mimicking artesunate treatment failure and unmasking functional hyposplenism. — 科研速览 Science Skim