Tissue integration in the CAM assay, collagen intensity and near-interface cell density data for novel emulsion electrospun DegraPol®-Bakuchiol fiber meshes that were characterized by FTIR and for fiber thickness and pore size.

To develop bioactive electrospun membranes capable of controlled Bakuchiol release, we engineered an emulsion-electrospun DegraPol® (DP) polymer mesh. The structural integrity of the scaffolds was characterized through detailed fiber morphology and porosity analysis. FTIR spectra were taken. To evaluate the biological response in vivo, the Bakuchiol functionalized meshes were integrated into the chorioallantoic membrane (CAM) assay of the avian embryo. Tissue interaction was assessed via Masson-Goldner trichrome staining, providing semi-quantitative data on tissue integration and collagen deposition intensity. Furthermore, total cell density within the immediate peri‑implant microenvironment was quantified using Haematoxylin-Eosin (H&E) histological sections. In addition, the bacterial adhesion on the scaffold was tested with a Staphylococcus aureus strain. All experimental groups were evaluated against pure DP fiber meshes as a control to isolate the specific effects of Bakuchiol.