Radiation-free or Chemo-free: Rethinking the Best Strategy for PD-L1-High, Unresectable Stage III NSCLC.

This article discusses the emerging radiotherapy-free and chemo-free strategies in PD-L1-high, unresectable stage III NSCLC, reviewing the Evolution trial and comparing it with existing treatments. We highlight the need for further research to validate these approaches and ensure safe de-escalation without compromising curability.