Early clinical experience with a novel single-port robotic system for mediastinal tumor resection: A feasibility and safety assessment.

OBJECTIVE: To evaluate the feasibility and perioperative safety of anterior mediastinal tumor resection using a flexible single-port robotic system (SR-ENS-600) via a single subxiphoid approach. METHODS: This prospective single-center feasibility study included the first 4 consecutive patients undergoing anterior mediastinal tumor resection with the SR-ENS-600 system. The primary end point was successful completion of resection without conversion or major device malfunction. Secondary end points included operative metrics, intraoperative safety, and 30-day postoperative outcomes. RESULTS: All procedures were completed via a single subxiphoid approach without conversion or device malfunction (technical success rate: 100%). Robotic manipulation time ranged from 62 to 116 minutes, and total operative time ranged from 89 to 131 minutes. Docking time decreased from 6 minutes in the first case to 2 to 3 minutes in subsequent cases. No intraoperative complications occurred. No Clavien-Dindo grade III or greater complications, reoperations, or 30-day readmissions were observed. CONCLUSIONS: Early clinical experience suggests that flexible single-port robotic resection of anterior mediastinal tumors via a subxiphoid approach is feasible and perioperatively safe in selected patients. Further evaluation in larger cohorts is warranted.