Factors associated with sexual quality of life among endometrial cancer survivors: A cross-sectional study.

PURPOSE: This study aimed to examine sexual quality of life (SQoL) and its associated factors among women with endometrial cancer, including menopausal symptoms, body image, sexual knowledge, and sexual function. METHODS: A cross-sectional observational study was conducted. A total of 113 women with endometrial cancer were recruited using convenience sampling. Data were collected through electronic questionnaires assessing demographic and clinical characteristics and key study variables. Hierarchical multiple regression analysis was performed to identify significant predictors of SQoL. The study was reported in accordance with the STROBE checklist for cross-sectional studies. RESULTS: The mean SQoL score was 68.86 (SD = 20.59), with 37.2% of participants reporting low to moderate levels. Significant factors associated with SQoL included body mass index (β = -0.17), receipt of radiotherapy (β = -0.28), menopausal symptoms (β = -0.20), body image distress (β = -0.26), and sexual function (β = 0.38). The final model explained 46% of the variance (p < 0.001), with sexual function emerging as the strongest predictor. CONCLUSIONS: SQoL among endometrial cancer survivors was associated with physiological, psychological, and functional factors. Sexual function showed the strongest association with SQoL, whereas receipt of radiotherapy and greater body image distress were associated with poorer SQoL. These findings highlight the importance of comprehensive survivorship care that includes routine assessment of sexual function, symptom management, body image support, and sexual rehabilitation. An integrated, multidisciplinary approach may help address the complex physical, psychological, and relational factors associated with sexual quality of life among endometrial cancer survivors.