NAT10 promotes keratinocyte-neutrophil crosstalk in atopic dermatitis.

Jia-Nan Wang, Xiao-Ming Meng

原始摘要（英文原文）· Original abstract

Atopic dermatitis (AD) is driven by complex interactions between keratinocytes and immune cells. In this issue of Cell Chemical Biology, Shao et al.1 identify that NAT10-dependent ac4C modification stabilizes Relb mRNA in keratinocytes, promoting chemokine production, neutrophil recruitment, and dermatitis progression.

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