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◆ Cell reports2026-09-21

Tumor growth going FAR with KRAS FARnesylation-induced phase separation.

Sidhant Kalia, Stéphan Vagner

原始摘要(英文原文)· Original abstract
RAS at the plasma membrane relay signals from cell-surface receptors to intracellular pathways. In Cell, Wang et al.1 show that farnesylation drives KRAS cytoplasmic condensation, contributing to its maturation. They identify statins as candidates to overcome resistance to KRAS-targeted therapies.
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Tumor growth going FAR with KRAS FARnesylation-induced phase separation. — 科研速览 Science Skim