Targeting senescent cells with dipeptidyl peptidase 4-CAR-NK cells alleviates liver fibrosis and reverses metabolic dysfunction.
Rui Hua, Kang Xu, Huan Peng, Kunda Liu, Nan Long, Chenye Zeng, Yida Wang, Yannan Guo, Zhao Wang
原始摘要(英文原文)· Original abstract
Selective elimination of senescent hepatocytes by DPP4-CAR-NK cells could rescue liver fibrosis; therefore improving liver function and metabolic homeostasis in CCl4-induced liver fibrotic and naturally aged mice.