PROMIS in oncology: A review of current applications and practical considerations for clinical integration

Patient-reported outcome measures are essential in oncology, yet variation in measure quality, clinical utility, and implementation infrastructure has hindered their consistent use and implementation in routine care. The Patient-Reported Outcomes Measurement Information System (PROMIS) offers a standardized, psychometrically rigorous, and flexible framework for assessing symptoms and functioning across the cancer continuum. This review synthesizes current evidence of PROMIS use in oncology, highlighting its advantages, including precise and efficient assessment, reduced patient burden, and strong applicability across diagnoses, treatment phases, and demographic groups, while also examining potential strategies for integrating PROMIS to support monitoring and enhanced patient-clinician communication. Practical guidance is provided on domain selection, administration formats, visualization approaches, clinical interpretation, and responsive implementation strategies. Taken together, PROMIS represents a robust approach to person-centered cancer care, enabling early identification of unmet needs, individualized care planning, and longitudinal tracking which is critical in detecting clinically meaningful changes and guiding responsive, evidence-informed treatment decisions across the cancer trajectory.