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◆ memo - Magazine of European Medical Oncology2026-04-01· Medicine

Current surgical standards in the management of the axilla

Kerstin Wimmer, Florian Fitzal

原始摘要(英文原文)· Original abstract
Summary Axillary surgery in breast cancer has undergone a profound transformation in recent decades. While axillary lymph node dissection (ALND) was the unquestioned standard until the 1990s [1], associated morbidity including lymphedema rates as high as 25% in the affected arm [2], led to the widespread adoption of sentinel lymph node biopsy (SLNB). Recent data now suggest that even SLNB may be safely omitted in selected low-risk patients. This article reviews the evolution of axillary management, summarizes pivotal evidence from the INSEMA, SOUND and BOOG 13-08 trials, and discusses the clinical implications, limitations, and future directions of this ongoing de-escalation process.
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Current surgical standards in the management of the axilla — 科研速览 Science Skim