KangDuo surgical robot KD-SR-01 versus da Vinci Xi in robot-assisted colorectal cancer resection: oncologic outcomes at three years in a multicenter randomized trial.

BACKGROUND: Earlier results from a multicenter randomized trial showed that colorectal cancer resection with KangDuo surgical robot KD-SR-01 (KD) and da Vinci Xi (DV) had similar perioperative and pathological outcomes, whereas long-term oncologic outcomes remained uncertain. METHODS: Three-year follow-up data were analyzed for the full 100-patient cohort of the multicenter randomized trial (KD, n = 50; DV, n = 50). The long-term endpoints were disease-free survival (DFS) and overall survival (OS). RESULTS: Median follow-up in both groups was 37 months (interquartile range [IQR], 34-40). Kaplan-Meier-estimated 3-year DFS rates were 85.3% for KD (95% confidence interval [CI], 71.5%-92.7%) and 85.5% for DV (95% CI, 71.9%-92.8%, log-rank P = 0.995). Kaplan-Meier-estimated 3-year OS rates were 100.0% for KD (95% CI, 100.0%-100.0%) and 94.0% for DV (95% CI, 82.4%-98.0%, log-rank P = 0.606). After covariate adjustment, the DFS hazard ratio (HR) comparing KD with DV was 0.918 (95% CI, 0.301-2.798; P = 0.881). CONCLUSIONS: At 3 years, no significant between-group differences in DFS or OS were detected between patients assigned to KD-SR-01 and da Vinci Xi for colorectal cancer resection.