Tissue Micro‐Coring Is a Safe and Effective Option for the Treatment of the Nasolabial Fold, Marionette, and Perioral Rhytids

BACKGROUND: Non-surgical treatment of the aging lower face remains a therapeutic challenge. Tissue Micro-Coring Technology (MCT) is a novel technology that permits the non-surgical removal of skin as micro-cores, tightening skin and inducing collagen and elastin. OBJECTIVE: To evaluate safety and efficacy of MCT for the treatment of the aging lower face. METHODS: This retrospective, single-site study assessed outcomes for subjects treated with MCT. Assessments included the change from baseline in Lemperle Wrinkle Severity Scale (LWSS) assessed for the nasolabial folds (NLF), marionette lines, lip lines, and global esthetic improvement scale (I-GAIS). RESULTS: A total of 10 patients met the study criteria. Mean (SD) I-GAIS was 1.7 (0.36), and mean (SD) change from baseline in LWSS for NLF, marionette lines, and lip lines were 1.1 (0.46), 1.3 (0.3), and 0.6 (0.35), respectively. Most subjects had some improvement in LWSS across all three treatment areas, with many experiencing > 1-point improvements. LIMITATIONS: Limitations include the retrospective study design, small study population, and single-sex population. CONCLUSION: In the real-world setting, MCT leads to improvements in global appearance and wrinkle severity. MCT is an effective alternative to injectable fillers for the treatment of nasolabial fold and marionette and perioral lines.