Stephany Celeste Gutiérrez-Ruíz, Alejandra Romero‐Montero, Héctor Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, F. Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, D. Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez
ABSTRACT Curcumin is a natural polyphenol derived from Curcuma longa with well‐documented anti‐inflammatory, antioxidant, antimicrobial, and wound‐healing properties. However, its clinical application in dermatology remains limited due to its low water solubility, low stability, and limited skin penetration. Recent advances in nanotechnology have enabled the development of curcumin delivery systems designed to improve dermal bioavailability, stability, and controlled release. Our novelty lies in integrating bibliometric analyses with a translational emphasis on food‐grade nanocarriers. This review highlights the therapeutic relevance of curcumin in major skin conditions, such as psoriasis, atopic dermatitis, acne, wound healing, burns, and skin cancer, with an emphasis on lipid‐ and polymer‐based nanoformulations, such as liposomes, niosomes, solid lipid nanoparticles, nanostructured lipid carriers, and hydrogel‐based platforms. Furthermore, the bibliometric analysis highlights a growing scientific interest in curcumin nanotherapies, although clinical evidence remains limited. In general, curcumin nanoformulations represent promising strategies for topical dermatological applications, but further clinical validation and regulatory development are required to support their application in therapeutic products.