Gerile Zhang, Riletu Ge, Jing Gao, Yuzhen Zhou
Clinical presentations mimicking angina pectoris, accompanied by secondary ECG changes such as deep T-wave inversions and QT-interval prolongation, are relatively uncommon in patients with hypoparathyroidism. A thorough evaluation combining clinical presentation, characteristic signs, and laboratory investigations can significantly reduce the rate of misdiagnosis.
OBJECTIVE: To promptly identify electrocardiographic (ECG) manifestations, including deep T-wave inversions and QT-interval prolongation, secondary to hypoparathyroidism and to improve its diagnostic accuracy and therapeutic management.
METHODS: We conducted a comprehensive analysis of the integrated treatment for a patient presenting with chest pain and evolving ECG changes secondary to hypoparathyroidism, supplemented by a review of the relevant literature.
RESULTS: In this case, a patient diagnosed with hypoparathyroidism presented with chest pain and dynamic ECG alterations. Following a confirmed diagnosis, treatment with calcium supplementation successfully alleviated the patient's chest pain and resulted in the complete normalization of the previously abnormal ECG findings.
CONCLUSION: Clinical presentations mimicking angina pectoris, accompanied by secondary ECG changes such as deep T-wave inversions and QT-interval prolongation, are relatively uncommon in patients with hypoparathyroidism. A thorough evaluation combining clinical presentation, characteristic signs, and laboratory investigations can significantly reduce the rate of misdiagnosis.