Mahlatse Cordelia Kgokolo, Lesedi Makgwethele Nevondo, Michaela Beetge, R A G Khammissa
Pemphigus vulgaris may demonstrate differential treatment responses across disease sites. In this case, cutaneous lesions responded to high-dose corticosteroids, whereas refractory oral disease required rituximab to achieve remission, highlighting the need for individualized, multimodal therapy to achieve sustained disease control.