Musawer Khan, Safia Bibi, Zarafshan Khan, F N U Ruqayya, Arwaa Chaudhry, Nauman Khan, Alamzaib Khan, Kamil Ahmad Kamil, F N U Zainullah
A 70-year-old male with CLL presented with dengue fever complicated by AKI. A diagnostic challenge arose from overlapping features. Investigations showed leukocytosis, lymphocytosis, anemia, thrombocytopenia, positive Anti-Dengue IgM, and renal impairment. Managed with supportive care, ibrutinib, and monitoring, with improvement. At the 3-month follow-up, he remained stable, highlighting the importance of multidisciplinary management.