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◆ Chemistry - An Asian Journal2025-10-20· Chemistry

Synthesis of Selenylated Pyridones via Bromide‐Catalyzed Direct C( <i> sp <sup>2</sup> </i> )─H Bond Selenylation of Pyridones With Diselenides

Jinhui Cai, Wenting Zhang, Zijing Xing, Wei Zhang, Depeng Yang, Yutao Peng, Zi Yang, Mingming Yu, Feng Zhao

原始摘要(英文原文)· Original abstract
A straightforward and sustainable platform for the efficient assembly of selenylated pyridones with pyridones and diselenides enabled by a cheap and green bromide catalyst was successfully reported. This method was highlighted by its readily available starting materials, metal-free, stoichiometric oxidant-free, simple catalytic system, and wide functional group compatibility. The potential synthetic utility of this strategy was demonstrated by its scalable-up reaction and diverse transformations. The preliminary mechanistic experiments revealed that a radical pathway was possibly involved.
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Synthesis of Selenylated Pyridones via Bromide‐Catalyzed Direct C( <i> sp <sup>2</sup> </i> )─H Bond Selenylation of Pyridones With Diselenides — 科研速览 Science Skim