L. Castañeda-Losada, Michael Richter, Christophe Léger, Vincent Fourmond, Nicolas Plumeré
ABSTRACT Replacing fossil resources with renewable alternatives for chemical production requires highly integrated, energy‐efficient, and selective CO 2 utilization processes. Electroenzymatic CO 2 fixation offers a promising pathway, combining high energy efficiency with unparalleled product selectivity, making it a viable approach for synthesizing complex molecules. This review outlines the fundamental principles of bioelectrocatalytic CO 2 conversion using reductases and carboxylases, providing an overview of the available enzymes, their product range, and key thermodynamic and kinetic considerations. By highlighting both the potential and limitations of electrochemical CO 2 fixation, this review aims to inform future progress in the discovery, engineering, and application of CO 2 ‐converting enzymes, with the ultimate goal of realizing the full potential of electroenzymatic CO 2 fixation for the sustainable synthesis of fine and specialty chemicals.