Liyan Zhang, Yun Chen, Sylvestre Bonnet
Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years, this tunability has enabled precise control over their interactions with peptides and proteins, opening new avenues in therapeutic and analytical applications. This minireview provides a concise overview of the growing role of ruthenium complexes in protein science, with a focus on latest advances in protein targeting, inhibition, labelling, and sensing.