W. J. Wang, Chunpeng Qiu, Zhihao Zuo, Younan Wang, Jingyu Wang
ABSTRACT A transition‐metal‐free LiO t Bu‐promoted three‐component reaction for efficient synthesis of the triazolyl (thio)ureas has been reported. This reaction proceeded via the cyclocondensation of nitriles and azides in the presence of a base, followed by the interception of the triazolamine and triazole nitrogen anion intermediate using (thio)carbamoylimidazoles. This method is characterized by being transition‐metal‐free, a broad substrate scope, and mild reaction conditions.