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◆ Advanced science (Weinheim, Baden-Wurttemberg, Germany)2026-09-09

An Efficient Biological Codon Recognition Reservoir Computing System Based on Low-Energy Epitaxial Hf0.52Zr0.48O2 Ferroelectric Memristors.

Ying Liu, Jikang Xu, Yongqing Jia, Wenxuan Wang, Weifeng Zhang, Biao Yang, Xiaobing Yan

原始摘要(英文原文)· Original abstract
The large demand for information processing has stimulated interest in low-power and fast-storage hafnium-based ferroelectric memristors because of their ability to precisely control the state of the resistor by polarization flip-flop without the need for electroforming. However, there is still a lack of hafnium-based ferroelectric memristor with both high stability and ultra-low operating energy consumption, which are the basic conditions for efficient neural network computation with high recognition rates. This article introduces a high-quality epitaxially grown Pd/Hf0.52Zr0.48O2 (HZO) /La0.67Sr0.33MnO3/SrTiO3 ferroelectric memristor. The device offers high stability, such as multi-stage stable storage states (16-state retention time can exceed 104 s), high endurance performance (108 cycles), and stable pulse modulation. At the same time, the device has an ultra-low energy consumption of 121 fJ. In addition, the HZO memristor is capable of a wide range of synaptic behaviors and logic operations. Importantly, this work is the first to apply a reservoir computing network based on HZO memristors to the field of biological genetics. The network successfully achieves a biological codon recognition accuracy of over 97% via the dual-feature strategy. This work provides concrete system and design ideas for achieving low-cost and high-accuracy codon recognition in the biological field.
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An Efficient Biological Codon Recognition Reservoir Computing System Based on Low-Energy Epitaxial Hf0.52Zr0.48O2 Ferroelectric Memristors. — 科研速览 Science Skim