Zijian Wang, Chaoqi Chen, He Meng, He Lian, Xi Cui, Chao Zhang, Zhou Li
Abstract Piezoelectric materials have become a research hotspot in bioelectronic medicine due to their excellent electromechanical conversion properties. In particular, biodegradable piezoelectric materials can avoid the risk of secondary removal surgeries, revealing great potential in clinical applications. This review summarizes the types, mechanisms, and properties of representative degradable piezoelectric materials, including amino acids, peptides, polysaccharides, and synthetic polymers. The processing strategies and the progress of their application in biomedical applications are further demonstrated. Finally, challenges and perspectives of the development of degradable piezoelectric materials are also discussed.